Sicilia Express Release Date, Cast: When Is It Coming Out?

Sicilia Express is a 2025 Italian comedy-drama series streaming on Netflix. Directed by Marco Deufemia and written by Nastasha Baron, the show offers a delightful blend of humor and drama, following engaging stories with a captivating Italian backdrop and a talented cast.

Sicilia Express Plot:

Just days before Christmas, two nurses from Sicily—working long shifts in a bustling Milan hospital—stumble upon a shimmering, inexplicable portal tucked away in an abandoned alley. Already stretched thin balancing grueling hospital rotations with the ache of separation from their families back home, this magical find hints at extraordinary, life‑altering possibilities… though whether it will bring wonder or chaos remains anyone’s guess.

Sicilia Express Detail:

TV Series: Sicilia Express – Season 1
Streaming Network: Netflix
Director: Marco Deufemia
Writer: Nastasha Baron
Main Cast: Angelo Pisani, Alessia Spinelli, Giovanna Criscuolo
Genres: Comedy, Drama
Country of Origin: Italy
Language: Italian
Release Date: December 21, 2025 (Netflix)
Season Number: 1
Total Episodes: 5
Episode Runtime: 1 hour 25 minutes (85 minutes)
Also Known As: Sicily Express, Sicilia Express Netflix, Sicilia Express Season 1

Sicilia Express Cast:

• Angelo Pisani – Andrea

• Alessia Spinelli – Luisa

• Giovanna Criscuolo – Giovanna

• Salvatore Ficarra – Salvo

• Valentino Picone – Valentino

• Katia Follesa – Claudia

• Barbara Tabita – Maria Teresa

• Sergio Vastano – Sergio Perrone

• Massimiliano Tortora – Presidente del Consiglio

• Enrico Bertolino – Enrico

• Angelo Tosto – Giacalone

• Vincenzo Ficarra – Mario

• Anna Melato – Signora Elvira

• Giovanni Federico – Ferdinando

• Luigi Maria Rausa – Uzeda

• Giorgio Tirabassi – Alfredo

• Adelaide Massari – Aurora

• Alessandro Idonea – Giulio Giacalone

• Ambra Aparo – Fidanzata di Mario

• Marco Basile – Guglielmo

• Mimmo Mignemi – Carmelo (The Bad Guy, 2022)

• Miriam Galanti – Miriam